![Study targets kappa opioid receptor to develop more effective drugs for pain management | Anesthesiology | Washington University School of Medicine in St. Louis Study targets kappa opioid receptor to develop more effective drugs for pain management | Anesthesiology | Washington University School of Medicine in St. Louis](https://anesthesiology.wustl.edu/wp-content/uploads/2023/03/Tao-Che.jpg)
Study targets kappa opioid receptor to develop more effective drugs for pain management | Anesthesiology | Washington University School of Medicine in St. Louis
![Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion | Semantic Scholar Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/4d3293c2088da60abdac11b52d2ea3b4ecc4f433/11-Figure2-1.png)
Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion | Semantic Scholar
![Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12964-022-00833-3/MediaObjects/12964_2022_833_Figa_HTML.png)
Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text
![Frontiers | Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management Frontiers | Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management](https://www.frontiersin.org/files/MyHome%20Article%20Library/508023/508023_Thumb_400.jpg)
Frontiers | Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management
![Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0028390820304093-fx1.jpg)
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect
![Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0278584615000020-fx1.jpg)
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect
![Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation | Scientific Reports Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-021-88118-6/MediaObjects/41598_2021_88118_Fig7_HTML.png)
Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation | Scientific Reports
![Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol, Drug, and Food Addiction - ScienceDirect Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol, Drug, and Food Addiction - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0074774217301393-f03-01-9780128124734.jpg)
Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol, Drug, and Food Addiction - ScienceDirect
![Regulation of κ-Opioid Receptor Signaling in Peripheral Sensory Neurons In Vitro and In Vivo | Journal of Pharmacology and Experimental Therapeutics Regulation of κ-Opioid Receptor Signaling in Peripheral Sensory Neurons In Vitro and In Vivo | Journal of Pharmacology and Experimental Therapeutics](https://jpet.aspetjournals.org/content/jpet/338/1/92/F9.large.jpg)
Regulation of κ-Opioid Receptor Signaling in Peripheral Sensory Neurons In Vitro and In Vivo | Journal of Pharmacology and Experimental Therapeutics
![The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/949a9b01-3f7c-4aa7-bc00-2e80cd815320/jnc14612-fig-0005-m.jpg)
The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library
![IJMS | Free Full-Text | κ-Opioid Signaling in the Lateral Hypothalamic Area Modulates Nicotine-Induced Negative Energy Balance IJMS | Free Full-Text | κ-Opioid Signaling in the Lateral Hypothalamic Area Modulates Nicotine-Induced Negative Energy Balance](https://pub.mdpi-res.com/ijms/ijms-22-01515/article_deploy/html/images/ijms-22-01515-g005.png?1612372727)